The interleukin 1 gene family in systemic juvenile idiopathic arthritis
Patients with systemic Juvenile Idiopathic Arthritis (sJIA) have elevated serum levels of inflammatory cytokines. Treatment with interleukin-1 (IL-1) receptor antagonist (Anakinra) shows remarkable improvement in some sJIA patients. The hypothesis of this thesis is that genetic variations in IL-1 fa...
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University College London (University of London)
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565479 |