Molecular mechanism of the kinetochore-microtubule attachment in fission yeast

Kinetochore capture by the spindle microtubule is a crucial step required for chromosome biorientation. Any errors in this process would result in production of aneuploid progenies, a hallmark of human cancer. The Ndc80 complex, a conserved outer kinetochore complex, comprising four components, Ndc8...

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Bibliographic Details
Main Author: Hsu, K.-S.
Published: University College London (University of London) 2012
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565798