Study on the roles of O-acetylserine (thiol) lyase and thiol dependent reductase 1 of Leishmania
Thiol dependent reductase 1 (TDR1) of Leishmania has been implicated in both the activation of pentavalent antimonial drugs and in the generation of drug-thiol conjugates facilitating drug-resistance. Reverse genetic studies were carried out on TDR1 to elucidate the role of the enzyme and to assess...
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University of Glasgow
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.566417 |