Analysis of the function of Mad2B in the mammalian cell cycle

Mad2B (also called Rev7 or Mad2L2) is a regulatory subunit of DNA polymerase ζ that is involved in translesion DNA synthesis (TLS). Previous studies have implicated Mad2B in several cell functions including cell cycle regulation where it was shown to inhibit the Anaphase Promoting Complex (APC)/cycl...

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Bibliographic Details
Main Author: Kim, Ju-Hwan
Other Authors: Patel, Rajnikant
Published: University of Leicester 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568164