Lentiviral gene therapy for HIV using TRIM-cyclophilin restriction factors

Lentiviral vector delivery of anti-HIV elements could provide the basis of alternative therapies against HIV, potentially providing long term protection after a single intervention. Some primate species have evolved restriction factors formed by the fusion of TRIM5α and Cyclophilin A (TRIM5Cyp) foll...

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Bibliographic Details
Main Author: Chan, E.
Published: University College London (University of London) 2012
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568277