Development of novel mouse models to study the p53 tumour suppressor
TP53 is the most commonly mutated gene in all human cancers [Vogelstein, 1990] and co- ordinates many of the cellular responses to DNA damage. It is vitally important therefore that we gain a better understanding of the function and regulation of p53. Since a major consequence of p53 mutation is can...
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University of Liverpool
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569766 |