Evaluation of PAMAM dendrimers as delivery vehicles for platinum based anticancer drugs
Four carboxylate terminated half generation polyamdioamine (PAMAM) dendrimers (G3.5- G6.5) were conjugated with the active components of cisplatin, {Pt(NH3)2}2+, or oxaliplatin, {Pt(R,R-dach)}2+, to form dendrimer platinate complexes. The platinum content of the cisplatin containing complexes was me...
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University of Strathclyde
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.570593 |