Synthesis of azetidines and pyrrolidines : towards medicinal chemistry and organocatalysis applications
Room temperature iodocyclisation of homoallylamines stereoselectively delivers functionalised 2- (iodomethyl)azetidine derivatives in high yield. Increasing reaction temperature from 20 °C to 50 °C switches the reaction outcome to realise the stereoselective formation of functionalised 3-iodopyrroli...
| Main Author: | |
|---|---|
| Published: |
University of Birmingham
2013
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.571857 |