The genetic architecture of secretory PLA2 (sPLA2) genes and their impact on sPLA2 activity/mass and association with CHD risk

Secretory phospholipase A2 group (sPLA2) enzymes hydrolyze the sn-2 ester bond of phospholipids, producing lysophospholipids and free fatty acids. SPLA2s have been identified as biomarkers of atherosclerosis in observational and animal studies. The aim of this study was to identify functional varian...

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Bibliographic Details
Main Author: Exeter, H. J.
Published: University College London (University of London) 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572565