The cellular impact of diminished DNA origin licensing capacity and its potential therapeutic exploitation
Genomic instability underlies various diseases including cancer. The maintenance of genomic stability requires accurate replication of the genome, proper segregation of duplicated DNA to progeny cells, and the capacity to respond effectively to DNA damage. Early sections of this thesis focus on the...
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University of Sussex
2013
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572865 |