Study of Wolfram Syndrome in neuronal cell models

Wolfram Syndrome (WS) is a rare autosomal recessive disease characterised by insulin-dependent diabetes mellitus, optic nerve atrophy. The current study demonstrated that neuronal cells depleted of WFS1 protein, showed significantly elevated expression of the ER stress markers indicating an enhanced...

Full description

Bibliographic Details
Main Author: Gharanei, Seley
Published: University of Birmingham 2013
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.573523