Characterisation of ^L597V BRAF in cancer
BRAF is a component of the RAF/MEK/ERK signalling cascade which controls fundamental cellular activities, including proliferation, cell survival, differentiation and motility. Deregulation of this pathway is common in cancer and ~7% of cancers have a mutation in BRAF. Leu597 is the fifth most common...
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University of Leicester
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.574120 |