Towards the synthesis of alpha-cyclo peptide nucleic acid monomers
Peptide nucleic acids (PNAs) are potentially useful as mimics of DNA for gene therapy treatment of cancer and other genetic disorders. The original PNA molecule developed by Nielsen et al. lacks selectivity towards nucleic acid targets (DNA vs RNA) and the ability to incorporate new monomers for eac...
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Heriot-Watt University
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.575340 |