Semipinacol rearrangement of cis-fused β-lactam diols into bicyclic lactams

The 6-azabicyclo[3.2.1]octane ring system is found in a wide variety of biologically active natural and non-natural products. The aim of this project is to prepare the 7,8-diketo-6-azabicyclo[3.2.1]octane structure via a semipinacol rearrangement of ring-fused β -lactams. Chapter 1 introduces the pi...

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Bibliographic Details
Main Author: Betou, Marie
Published: University of Birmingham 2013
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.575624