Use of lux gene technology to investigate real-time in-situ interactions of bacterial pathogens with a model blood-brain barrier system

Bacterial bioluminescence has been shown to be an accurate real-time reporter of bacterial internalisation and a valid alternative to viable counts. A self-bioluminescent strain of the bacterial pathogen Neisseria meningitidis was used to develop and optimise an internalisation assay with a range of...

Full description

Bibliographic Details
Main Author: Grimshaw, K. L.
Published: University of the West of England, Bristol 2012
Subjects:
600
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576176