Sphingosine kinases : evaluation of therapeutic potential using prostate cancer cell models
Sphingosine kinase 1 and 2 (SK1 and SK2) catalyse the formation of the bioactive lipid sphingosine 1-phosphate. Alterations in SK1 function have been implicated in human prostate cancer, being involved in the acquisition of therapy resistance and progression to androgen independence, two major issue...
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University of Strathclyde
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576391 |