Generation and testing of a novel multimeric C3d based adjuvant
C3d, a proteolytic fragment of complement component 3, is a ligand for complement receptor 2 (CR2) expressed by B cells. When antigen (Ag) coated with C3d cross-links CR2 and Ag specific B cell receptor, the threshold for B cell activation is lowered resulting in an enhanced response to Ag. This mad...
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University of Newcastle Upon Tyne
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576537 |