The identification of new regulators of phase II detoxification gene expression by a genome-wide RNAi screen in Caenorhabditis elegans
The phase II detoxification system is an important cellular defence against free radicals and xenobiotics and is induced in response to stress. Conserved bZIP transcription factors such as Nrf2 in mammals and SKN-1 in Caenorhabditis elegans are required for the regulation of phase II detoxification...
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University of Newcastle Upon Tyne
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577175 |