High throughput measurement of antibody and complement mediated immunity to meningococcal disease

The accepted correlate of protection for meningococcal disease is serum bactericidal activity. The importance of bactericidal activity was established by Goldschneider et al. (1969) who demonstrated an inverse relationship between disease incidence and bactericidal titres of >1 :4. The importance...

Full description

Bibliographic Details
Main Author: Brookes, Charlotte
Published: Open University 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578658