New genes involved in the synthesis of diphthamide, a modification of eukaryotic translation elongation factor 2 with roles in diphtheria disease and ovarian cancer formation
Diphthamide, the target of Diphtheria toxin, is a unique post-translational modification on His₆₉₉ (S. cerevisiae) of translation elongation factor 2 (eEF2) found in eukarya and archaea. It serves as the unique target for bacterial ADP-ribosylating toxins such as Diphtheria Toxin, Exotoxin A and Cho...
Main Author: | Uthman, Shanow |
---|---|
Other Authors: | Schaffrath, Raffael; Giorgini, Flaviano |
Published: |
University of Leicester
2013
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579197 |
Similar Items
-
On diphtheria
by: Inglis, J.
Published: (1886) -
The modern treatment of diphtheria
by: Hodgson, Albert Ernest
Published: (1911) -
A Study of Diphtheria
by: Zamiri, I.
Published: (1973) -
Etiology and treatment of diphtheria
by: Alexander, William
Published: (1891) -
Clinical notes on diphtheria
by: Cowie, Hugh G.
Published: (1900)