The role of the signalling protein XLalphas in cardiovascular control in mice

Loss of the signalling protein XLαs in mice leads to a lean phenotype characterised by increased energy expenditure due to elevated sympathetic nervous system (SNS) stimulation of brown adipose tissue. XLαs is the protein produced from the Gnasxl transcript of the imprinted Gnas locus, and has a res...

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Bibliographic Details
Main Author: Nunn, Nicolas
Other Authors: Barrett-Jolley, Richard; Plagge, Antonius
Published: University of Liverpool 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579312