Step-efficient asymmetric approaches to saturated nitrogen heterocycles
An imino-aldol reaction between phenyl chlorovalerate and a variety of (S)-tert butylsulfinimines was developed which gave consistently high diastereoselectivites of up to 95:5:0:0 dr and yields of up to 87%. In several cases, single crystal X-ray crystallography confirmed the stereochemistry of the...
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University of Southampton
2012
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581471 |