Synthesis and applications of oligonucleotides containing 2'-modified nucleosides
This thesis describes the synthesis and applications of chemically modified oligonucleotides, principally those containing modifications at the 2´-position of ribose. One application is their use in triplex-forming oligonucleotides (TFOs). DNA triplexes are formed by the binding of a TFO to a DNA du...
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University of Southampton
2012
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581475 |