The asymmetric synthesis and reactions of α-functionalised organometallic reagents

This thesis describes the development of new methods for the asymmetric synthesis of α-alkoxy and α-amino organometallic reagents. Two approaches were taken: (i) sulfoxide → magnesium exchange; (ii) asymmetric lithiation-trapping using chiral bases. A review of this area is provided in Chapter One....

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Bibliographic Details
Main Author: Rayner, Peter
Other Authors: O'Brien, Peter
Published: University of York 2013
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581694