Modulation of canonical Wnt signalling in mesenchymal stem cells using a GSK3beta inhibitor

Multipotent stromal cells/mesenchymal stem cells (MSCs) can differentiate into multiple lineages including osteogenic and adipogenic cells. Wnt signalling has been implicated in controlling MSC fate, but the mechanism is unclear and apparently conflicting data exists. Here I show that a glycogen syn...

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Bibliographic Details
Main Author: Cook, David
Other Authors: Genever, Paul ; O'Shea, Patrick
Published: University of York 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581724