The role of NSP1 in rotavirus pathogenesis

NSP1, a non-structural protein encoded by rotavirus gene segment 5, has been suggested as a virulence determinant for rotavirus and to function as an antagonist of the interferon signalling pathway. Although non-essential for rotavirus replication in cell culture, and is the least conserved in all r...

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Bibliographic Details
Main Author: Zhang, Fan
Published: University of Warwick 2012
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582299