The role of Vav proteins in macrophage morphology and migration

The Rho family GTPases are key signalling components that regulate the cytoskeleton and adhesion during cell migration. The Vav family of proteins act as guanine nucleotide exchange factors for several Rho GTPases. There are three isoforms of Vav expressed in mammalian cells: Vav1, the expression of...

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Bibliographic Details
Main Author: Bhavsar, Parag Jayprakash
Published: University College London (University of London) 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582582