Development of a PhiC31 system for functional characterisation of cis-regulatory elements in reporter transgenic zebrafish
Current methods to study enhancers in vivo involved integrating DNA sequences into the genome in a random position, in zebrafish the transposase Tol2 is utilised. However, this random genome integration can result in position effects which cause variations in reporter gene expression patterns preven...
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University of Birmingham
2013
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583205 |