Intramolecular benzyne trapping in synthesis of a Vitamin E precursor

Intramolecular benzyne trapping by alcohols have been applied to the synthesis of a series of racemic chromans. The theme of this project was to utilise this technique in the synthesis of the precursor, (/)-8-iodo-6-methoxy-2,5,7-trimethyl chroman-2-methanol, to the natural product Vitamin E. The ra...

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Bibliographic Details
Main Author: Xu, Qing
Published: Cardiff University 2004
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583504