Synthesis and biological characterisation of HPMA copolymer-mannose conjugates designed for intracellular delivery of anti-leishmanial compounds to macrophages
<italic>Visceral leishmaniasis</italic> is the second largest parasitic killer in the world (after malaria) with 59,000 deaths annually. The parasite resides in macrophages, within a compartment called the parasitophorous vacuole, but many anti-leishmanial drugs are toxic and poorly effe...
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Cardiff University
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584257 |