Molecular mechanisms of human thyroid tumorigenesis
Thyroid cancer is the commonest endocrine malignancy. Several of the initiating genetic events in thyroid tumorigenesis have been identified, although the exact molecular mechanisms are unclear. Our thyrocyte model has demonstrated that p16INK4A is up-regulated in RAS-induced colonies which resemble...
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Cardiff University
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584462 |