Elucidating ryanodine receptor domain interactions in sudden cardiac death : towards the development of novel therapeutic strategies
Interdomain Interactions within the complex three-dimensional architecture of the cardiac ryanodine receptor (RyR2) are pivotal in channel regulation. Acquired or genetic abnormalities that perturb these stabilising intra-molecular interactions are pathogenic. This laboratory identified the interact...
| Main Author: | |
|---|---|
| Published: |
Cardiff University
2009
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584681 |