Anti-epidermal growth factor receptor (EGFR) therapy modelled in the mouse

Despite advances in response prediction to epidermal growth factor receptor (EGFR) targeted therapy in colorectal cancer there remain unknown factors determining the clinical outcome in patients with K-RAS wild type tumours in the absence of mutations activating B-RAF or PIK3CA/PTEN signalling. In a...

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Bibliographic Details
Main Author: Shaw, Paul H. S.
Published: Cardiff University 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584863