Physiological responses to genomic instability
Abnormalities in the cellular senescence programme may contribute to premature ageing and cancer predisposition. Primary human cells have a limited proliferative capacity, entering a state of irreversible growth arrest/senescence arising from telomere attrition (replicative senescence). Stress-induc...
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Cardiff University
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584893 |