Role of Claudin-5 in the progression of human breast cancer

A key step in metastasis is the interaction and penetration of the vascular endothelium by cancer cells. Tight Junctions (TJ) are located between the cancer epithelial cells themselves functioning in an adhesive manner, and between the endothelial cells. They represent a critical barrier which the c...

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Bibliographic Details
Main Author: Escudero-Esparza, Astrid
Published: Cardiff University 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584980