Regulation of transforming growth factor beta-1 signalling in the renal proximal tubular epithelial cells

The data presented shows that IL-1beta has a biphasic effect on PTC TGF-beta signalling, with early NF-kappaB-mediated inhibition and delayed sensitization via an autocrine IL-6 loop, and possibly also via an autocrine IL-6 loop, and possibly also via a switch from NF Kappa B p52/p50 heterodimer to...

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Bibliographic Details
Main Author: Luo, Dong-Dong
Published: Cardiff University 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.585055