Deciphering the link between PTPN22 and autoimmunity
Recent genetic studies have linked a C to T single nucleotide polymorphism (SNP) in the protein tyrosine phosphatase (PTP) non-receptor type 22 (PTPN22) to several autoimmune diseases (ADs). This changes amino acid at position 620 from an Arginine (R) to a Tryptophan (W) in the protein, Lyp. Lyp is...
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Cardiff University
2011
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.585182 |