A study of the role of presenilin (1) in regulating synaptic function at hippocampal synapses
Synapse dysfunction is emerging as a major factor in the pathogenesis of Alzheimer’s disease (AD). Key insights into the pathological mechanisms have been provided through studies of familial AD (FAD) genes. Mutations in the PSEN1 gene account for the vast majority of FAD cases, which are typified b...
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University College London (University of London)
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.587588 |