Synergistic transcriptional regulation of collagenase gene expression in chondrocytes
The proteolytic degradation of articular cartilage in load-bearing joints is a key pathological step in the progression of arthritis, a process mediated by enzymes called collagenases (specifically MMP-1 and MMP-13). My research has focused on the transcriptional regulation of these enzymes in carti...
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University of Newcastle upon Tyne
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588267 |