A short total synthesis of (±)-paroxetine and a formal asymmetric synthesis of (–)-paroxetine
Paroxetine, a selective serotonin reuptake inhibitor, is a potent drug used for the treatment of depression for more than 20 years. Although numerous syntheses have been reported for this molecule, the manufacturing process still uses a resolution step, as it remains the shortest way to access parox...
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University of Southampton
2013
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588896 |