Development of viral & non-viral episomal vectors for gene therapy applications

Gene therapy consists of methods which attempt to repair or replace defective genes responsible for disease, or to add genes to a therapeutic effect. To achieve this, two episomally maintained recombinant viral vectors have shown promising results: integration-deficient lentiviral vectors (IDLVs), a...

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Bibliographic Details
Main Author: Kymalainen, Hanna
Published: University of London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589000