Functional characterisation of genetic variants associated with malignant hyperthermia
Mutations in the skeletal muscle sarcoplasmic reticulum calcium release channel (RYR1) have been identified in association with malignant hyperthermia(MH)and exertional heat stroke(EHS). MH is a pharmacogenetic disorder in which hypermetabolism is triggered upon exposure to volatile anaesthetics. MH...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Leeds
2013
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589293 |