Antisense-mediated myostatin downregulation by destructive exon skipping using 2'O-methyl RNA and morpholino oligomers in skeletal muscle cells and animal products
Myostatin is a negative regulator of muscle mass, and several strategies are being developed to knock down the expression of the myostatin gene as a means to bring about improvements in muscle wasting conditions, including Duchenne muscular dystrophy (DMD). Improved muscle regeneration in the absenc...
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University of London
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589410 |