Computational modelling of G protein-coupled receptors

G protein-coupled receptors (GPCRs) comprise the most "drugable" family of transmembrane proteins, GPCRs share a common structural template and a general mechanism of signal transduction, but vary greatly in sequence conservation, ligand recognition and function. The current set of class A...

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Bibliographic Details
Main Author: Taddese, Bruck
Published: University of Essex 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589439