Mathematical modelling of chromosome replication and replicative stress

Previous theoretical work on DNA replication neglected how the starting points (origins) take their place and how replication time is a ected when origins fail to activate. It is however crucial that origin loci are chosen so that too large gaps between them are avoided; otherwise the time until com...

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Bibliographic Details
Main Author: Karschau, Jens
Published: University of Aberdeen 2013
Subjects:
530
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589508