Investigating the transcriptional control of Dnmt3L and post-transcriptional control of Dnmt1

In this thesis I present an investigation into mechanisms which regulate the expression of the DNA methyltransferase family members DNMT3L (a co-factor for de novo methylation) and DNMTl (the maintenance methyltransferase). I present work demonstrating the involvement of DNA methylation in the regul...

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Bibliographic Details
Main Author: Rutledge, Charlotte Emily
Published: University of Ulster 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589755