Pyruvate Dehydrogenase Kinase (PDK): An attractive target for anticancer therapy
Cancer cells are highly dependent on glycolysis. which provides protection against the hypoxic tumour microenvironment. Colorectal cancer cells have been reported to undergo increased glycolysis, the so-called 'Warburg's effect'. Previous research in our laboratory revealed increased...
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University of Leeds
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590158 |