The effect of tumour necrosis factor-alpha on airways smooth muscle contractility
A major characteristic of asthma is a hyper-responsiveness of the bronchial smooth muscle. This hyper-responsiveness is associated with an activation of inflammatory cells, such as neutrophils, which release the cytokine TNF-α. In vivo exposure of human airways to aerosolised TNF-α produces an incre...
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University of Aberdeen
1999
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593267 |