Human renal lipoxygenases : implications for papillary necrosis

The long-term administration or abuse of analgesics and therapeutic doses of non-steroidal anti-inflammatory drugs have been implicated in renal papillary necrosis (RPN). Several drugs implicated in RPN undergo metabolic activation, via prostaglandin synthetase (PGS) and / or lipoxygenase (LO) syste...

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Bibliographic Details
Main Author: Stewart, Victoria C.
Published: University of Aberdeen 1995
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593514