Studies towards the efficient isolation and purification of analogues of amphotericin B from Streptomyces nodosus
Amphotericin B, produced by Streptomyces nodosus, is a medically important antifungal that is also active against Leishmania parasites. However, its use is severely limited by its toxicity. Treatment would be much more effective if non-toxic analogues of amphotericin B were available. Genetic manipu...
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University of Leicester
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593686 |